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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?

A) Change glipizide to insulin.
B) Increase glipizide to 20 mg twice daily.
C) Change glipizide to metformin.
D) Continue with glipizide and add metformin.

2. A pharmacy student on rotation in a community health clinic states that he saw medical charts outside exam rooms in the box on the door. He wants to know if this conforms to the Health Insurance Portability and Accountability Act (HIPAA) privacy rule. What is the best response?

A) No, patient charts must be kept in a secure location at the nurses' station or in the room with the patient
B) No, patient charts may not be placed outside an exam room door
C) Yes, if the clinic removes the patient's name from the outside of the chart and places the chart in an unlabeled bin
D) Yes, provided that the clinic takes reasonable and appropriate measures to protect the patient's privacy

3. A 65-year-old Woman presents with complaints of Worsening incontinence associated with sneezing and coughing, as well as itching in the genital area. Physical examination reveals some vaginal atrophy. A pad test is positive, post void residuals average 5 mL, and urinalysis is normal. Which of the following is the best treatment option for this patient?

A) Tamsulosin
B) Vaginal estrogen cream
C) Bethanechol
D) Tolterodine

4. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?

A) ALT less than three times the upper limit of normal
B) Absence of alpha-fetoprotein
C) Absence of cryoglobulinemia
D) HCV RNA below the lower limit of quantification

5. A prospective randomized study is being developed to evaluate the effects of steroids on mortality in patients who are admitted for head injury Patients will be randomly assigned to receive 48 hours of methylprednisolone or placebo. The study will have an 80% power to detect a 2% difference in mortality. Which of the following is an appropriate null hypothesis for this study?

A) Methylprednisolone will increase mortality by 2% compared with placebo.
B) Methylprednisolone will have a 20% reduction in mortality compared with placebo.
C) Methylprednisolone and placebo are not different with respect to effect on mortality.
D) Methylprednisolone reduces mortality in head injury patients.

Solutions: